Lucio Cocco Selected Research

Acute Erythroblastic Leukemia (Erythroleukemia)

9/2017	Nuclear Localization of Diacylglycerol Kinase Alpha in K562 Cells Is Involved in Cell Cycle Progression.
11/2014	A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression.
6/2014	PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells.
3/2009	Involvement of nuclear PLCbeta1 in lamin B1 phosphorylation and G2/M cell cycle progression.
3/2007	Inositide-dependent phospholipase C signaling mimics insulin in skeletal muscle differentiation by affecting specific regions of the cyclin D3 promoter.
11/2006	Proteomic-based analysis of nuclear signaling: PLCbeta1 affects the expression of the splicing factor SRp20 in Friend erythroleukemia cells.
6/2005	Nuclear phospholipase C beta1 (PLCbeta1) affects CD24 expression in murine erythroleukemia cells.
1/2003	Engagement of PI-3-kinase mediated protein kinase C zeta activation in protecting Friend cells from ionizing radiation-induced apoptosis.
5/2002	Nuclear PLCbeta(1) acts as a negative regulator of p45/NF-E2 expression levels in Friend erythroleukemia cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Lucio Cocco Research Topics

Disease

55	Neoplasms (Cancer) 03/2022 - 01/2002
11	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 09/2015
11	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2022 - 05/2007
9	Acute Erythroblastic Leukemia (Erythroleukemia) 09/2017 - 05/2002
8	Breast Neoplasms (Breast Cancer) 01/2021 - 12/2004
8	Leukemia 01/2019 - 02/2005
7	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021 - 01/2005
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 11/2016
4	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2014
4	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 01/2016
3	Glioma (Gliomas) 03/2022 - 03/2007
3	Brain Diseases (Brain Disorder) 02/2022 - 01/2016
3	Myotonic Dystrophy (Dystrophia Myotonica) 01/2017 - 07/2012
3	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 08/2014 - 09/2008
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 03/2011 - 08/2008
2	Adenocarcinoma 01/2022 - 01/2020
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 01/2021
2	Hypoxia (Hypoxemia) 01/2021 - 09/2010
2	Infections 01/2020 - 12/2017
2	Disease Progression 01/2020 - 02/2016
2	Osteosarcoma (Osteogenic Sarcoma) 01/2019 - 01/2006
2	Type 2 Diabetes Mellitus (MODY) 05/2014 - 01/2012
2	Acute Promyelocytic Leukemia 05/2014 - 02/2010
2	Hematologic Neoplasms (Hematological Malignancy) 08/2013 - 01/2011
2	Carcinogenesis 12/2012 - 08/2006
2	Astrocytoma (Pilocytic Astrocytoma) 07/2010 - 03/2007
1	Glioblastoma (Glioblastoma Multiforme) 03/2022
1	Laminopathies 02/2022
1	Inflammation (Inflammations) 01/2022
1	Arteriovenous Fistula 01/2022
1	COVID-19 01/2020

Drug/Important Bio-Agent (IBA)

10	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2021 - 10/2005
8	Type C PhospholipasesIBA 03/2022 - 05/2002
8	Pharmaceutical PreparationsIBA 01/2020 - 06/2006
8	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2006
7	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 03/2011
7	Phosphotransferases (Kinase)IBA 07/2020 - 09/2008
6	EnzymesIBA 01/2022 - 07/2010
6	IsoenzymesIBA 12/2021 - 01/2002
6	Glycogen Synthase Kinase 3IBA 01/2021 - 10/2009
6	Phospholipase C betaIBA 11/2020 - 05/2002
6	Protein Isoforms (Isoforms)IBA 07/2020 - 03/2007
5	BerberineIBA 01/2022 - 12/2017
5	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2020 - 01/2006
5	Cyclin D3IBA 11/2020 - 11/2006
4	Biological ProductsIBA 02/2022 - 01/2011
4	Lamin Type B (Lamin B)IBA 02/2022 - 03/2009
3	Mechanistic Target of Rapamycin Complex 1IBA 01/2022 - 07/2014
3	Protein Kinase CIBA 11/2020 - 03/2009
3	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 01/2006
3	MicroRNAs (MicroRNA)IBA 12/2017 - 09/2015
3	NF-kappa B (NF-kB)IBA 01/2016 - 02/2005
3	Hormones (Hormone)IBA 01/2016 - 09/2011
3	Azacitidine (5 Azacytidine)FDA Link 01/2016 - 06/2013
3	ErbB Receptors (EGF Receptor)IBA 01/2016 - 09/2015
3	ChromatinIBA 08/2014 - 10/2005
3	TNF-Related Apoptosis-Inducing LigandIBA 02/2011 - 01/2006
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2008 - 12/2004
3	LigandsIBA 11/2008 - 12/2005
3	CytokinesIBA 04/2007 - 12/2004
2	nutlin 3IBA 01/2022 - 01/2019
2	Tumor Suppressor Protein p53IBA 01/2022 - 01/2022
2	epidermal growth factor receptor VIIIIBA 12/2020 - 01/2016
2	IronIBA 11/2020 - 03/2016
2	phosphatidylinositol 3,4,5-triphosphateIBA 04/2020 - 08/2006
2	Estrogen ReceptorsIBA 01/2020 - 11/2016
2	Metformin (Glucophage)FDA LinkGeneric 01/2018 - 09/2015
2	ResveratrolIBA 01/2018 - 12/2017
2	Fluorouracil (Carac)FDA LinkGeneric 01/2018 - 01/2018
2	Tamoxifen FDA LinkGeneric 01/2018 - 09/2011
2	Androgen Receptors (Androgen Receptor)IBA 01/2018 - 01/2016
2	CurcuminIBA 01/2018 - 12/2017
2	Gemcitabine FDA Link 01/2018 - 01/2018
2	beta CateninIBA 02/2017 - 05/2014
2	MTOR InhibitorsIBA 11/2016 - 10/2012
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 05/2014 - 02/2010
2	AntibodiesIBA 02/2011 - 03/2007
2	Small Interfering RNA (siRNA)IBA 09/2010 - 06/2005
2	LipidsIBA 09/2009 - 10/2002
2	AntigensIBA 08/2008 - 12/2004
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 06/2006 - 12/2004
1	LaminsIBA 02/2022
1	eprenetapoptIBA 01/2022
1	HematinicsIBA 01/2021
1	roxadustatIBA 01/2021
1	Phosphatidylinositol PhosphatesIBA 01/2021
1	Daunorubicin (Cerubidine)FDA LinkGeneric 12/2020
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 07/2020
1	DiglyceridesIBA 07/2020
1	Phosphatidylinositol 4,5-Diphosphate (Phosphatidylinositol 4,5 Diphosphate)IBA 04/2020
1	Phospholipids (Phosphatides)FDA LinkGeneric 04/2020
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2020
1	VitaminsIBA 01/2020
1	VaccinesIBA 01/2020
1	Trace Elements (Biometals)IBA 01/2020

Therapy/Procedure

36	Therapeutics 01/2022 - 01/2006
6	Drug Therapy (Chemotherapy) 01/2020 - 01/2006
2	Aftercare (After-Treatment) 01/2022 - 07/2010
2	Radiotherapy 01/2019 - 11/2011
1	TP protocol 12/2020